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James L Januzzi Selected Research

Left Ventricular Dysfunction

4/2024Effect of Empagliflozin on Heart Failure Outcomes After Acute Myocardial Infarction: Insights from the EMPACT-MI Trial.
8/2020Heart Failure With Reduced Ejection Fraction: A Review.
11/2018A Novel Paradigm for Sacubitril/Valsartan: Beta-Endorphin Elevation as a Contributor to Exercise Tolerance Improvement in Rats With Preexisting Heart Failure Induced by Pressure Overload.
1/2018Prognostic Value of High-Sensitivity Troponin T in Chronic Heart Failure: An Individual Patient Data Meta-Analysis.
3/2015Galectin-3 and mineralocorticoid receptor antagonist use in patients with chronic heart failure due to left ventricular systolic dysfunction.
1/2015Mineralocorticoid receptor antagonists modulate galectin-3 and interleukin-33/ST2 signaling in left ventricular systolic dysfunction after acute myocardial infarction.
11/2014Ideal cardiovascular health: associations with biomarkers and subclinical disease and impact on incidence of cardiovascular disease in the Framingham Offspring Study.
5/2013Characterization and prediction of natriuretic peptide "nonresponse" during heart failure management: results from the ProBNP Outpatient Tailored Chronic Heart Failure (PROTECT) and the NT-proBNP-Assisted Treatment to Lessen Serial Cardiac Readmissions and Death (BATTLESCARRED) study.
3/2013Improvement in structural and functional echocardiographic parameters during chronic heart failure therapy guided by natriuretic peptides: mechanistic insights from the ProBNP Outpatient Tailored Chronic Heart Failure (PROTECT) study.
11/2012Use of biomarkers to guide outpatient therapy of heart failure.
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James L Januzzi Research Topics

Disease

330Heart Failure
04/2024 - 04/2004
59Myocardial Infarction
05/2024 - 05/2002
50Cardiovascular Diseases (Cardiovascular Disease)
03/2024 - 02/2008
35Acute Coronary Syndrome
11/2023 - 05/2002
30Dyspnea (Shortness of Breath)
01/2022 - 12/2004
28Inflammation (Inflammations)
03/2024 - 02/2008
24Fibrosis (Cirrhosis)
12/2023 - 03/2010
22Type 2 Diabetes Mellitus (MODY)
04/2024 - 08/2017
22Coronary Artery Disease (Coronary Atherosclerosis)
12/2023 - 04/2004
21Cardiomyopathies (Cardiomyopathy)
05/2024 - 06/2008
19Chronic Renal Insufficiency
04/2024 - 05/2009
18Atrial Fibrillation
12/2023 - 08/2006
18Chest Pain (Chest Pains)
10/2023 - 06/2004
15Stroke (Strokes)
03/2024 - 08/2006
14Left Ventricular Dysfunction
04/2024 - 07/2005
13Ventricular Remodeling
11/2023 - 01/2013
12Necrosis
01/2021 - 05/2002
11Heart Diseases (Heart Disease)
12/2023 - 10/2004
11Hypertension (High Blood Pressure)
01/2023 - 05/2010
10Obesity
04/2024 - 04/2005
9Neoplasms (Cancer)
11/2023 - 09/2012
9Hemorrhage
09/2023 - 05/2002
8Breast Neoplasms (Breast Cancer)
01/2023 - 05/2011
8Diabetes Mellitus
01/2022 - 11/2007
7Renal Insufficiency (Renal Failure)
12/2023 - 05/2002
7Anemia
11/2023 - 06/2007
6Coronary Disease (Coronary Heart Disease)
05/2024 - 09/2008
6Diabetic Nephropathies (Diabetic Nephropathy)
02/2024 - 01/2022
6Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
01/2024 - 05/2009
6Cardiotoxicity
11/2023 - 05/2011
6Cardiac Arrhythmias (Arrythmia)
10/2023 - 04/2015
6Hypotension (Low Blood Pressure)
01/2022 - 04/2009
6Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
09/2016 - 08/2007
5Cardiac Sudden Death (Sudden Cardiac Arrest)
01/2023 - 06/2009
5Kidney Diseases (Kidney Disease)
01/2023 - 01/2006
5Chronic Obstructive Pulmonary Disease (COPD)
10/2022 - 07/2006
5Pathologic Constriction (Stenosis)
01/2022 - 11/2014
5Overweight
01/2021 - 04/2005
5Critical Illness (Critically Ill)
02/2016 - 08/2004
5Hypertrophy
04/2015 - 08/2013
4Chronic Kidney Failure (Chronic Renal Failure)
02/2024 - 12/2009
4Aortic Valve Stenosis (Aortic Stenosis)
12/2023 - 01/2018
4Mitral Valve Insufficiency (Mitral Regurgitation)
11/2022 - 03/2013
4Disease Progression
10/2022 - 03/2014
4COVID-19
07/2021 - 01/2020

Drug/Important Bio-Agent (IBA)

191Biomarkers (Surrogate Marker)IBA
04/2024 - 05/2002
124Brain Natriuretic Peptide (Natrecor)FDA Link
04/2024 - 08/2004
120pro-brain natriuretic peptide (1-76)IBA
04/2024 - 12/2004
83Natriuretic PeptidesIBA
04/2024 - 06/2004
41TroponinIBA
01/2024 - 02/2006
39Troponin T (Troponin T1)IBA
12/2023 - 12/2002
29empagliflozinIBA
04/2024 - 05/2017
22sacubitril and valsartan sodium hydrate drug combinationIBA
10/2023 - 01/2018
20Troponin IIBA
11/2023 - 12/2002
17Galectin 3 (LGALS3)IBA
01/2024 - 09/2006
15Glucose (Dextrose)FDA LinkGeneric
04/2024 - 01/2017
15CreatinineIBA
02/2024 - 05/2002
15C-Reactive ProteinIBA
10/2022 - 09/2008
14Sodium-Glucose Transport ProteinsIBA
04/2024 - 05/2017
14omega-Chloroacetophenone (Mace)IBA
03/2024 - 12/2014
13CanagliflozinIBA
02/2024 - 12/2019
12SodiumIBA
02/2024 - 08/2017
11Sodium-Glucose Transporter 2 InhibitorsIBA
03/2024 - 11/2017
11Proteins (Proteins, Gene)FDA Link
01/2024 - 08/2007
11Trinitrotoluene (TNT)IBA
01/2022 - 05/2002
10trans-crotonin (CTN)IBA
11/2023 - 12/2009
8Cystatin CIBA
01/2022 - 02/2011
7Lipoprotein(a)IBA
05/2024 - 11/2020
7SymportersIBA
04/2024 - 08/2017
7Peptides (Polypeptides)IBA
01/2024 - 04/2011
7Interleukin-33IBA
11/2023 - 07/2013
7Neprilysin (Neutral Endopeptidase)IBA
01/2021 - 08/2015
6insulin-like growth factor binding protein-related protein 1IBA
04/2024 - 11/2016
6InterleukinsIBA
01/2022 - 08/2007
6Mineralocorticoid Receptor AntagonistsIBA
01/2022 - 01/2015
5DiureticsIBA
04/2024 - 12/2010
5Oxygen (Dioxygen)IBA
04/2024 - 01/2017
5Growth Differentiation Factor 15IBA
11/2023 - 11/2014
5AlbuminsIBA
01/2023 - 01/2005
5Hemoglobins (Hemoglobin)IBA
10/2022 - 06/2007
5Trastuzumab (Herceptin)FDA Link
01/2020 - 05/2011
5Glycoproteins (Glycoprotein)IBA
01/2020 - 05/2002
5Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics)IBA
01/2020 - 01/2006
5Endothelin-1 (Endothelin 1)IBA
11/2018 - 04/2011
5Interleukin-1 Receptors (Interleukin 1 Receptor)IBA
05/2010 - 08/2007
4Uric Acid (Urate)IBA
04/2024 - 01/2022
4LigandsIBA
11/2023 - 07/2013
4AnthracyclinesIBA
01/2023 - 05/2011
4Valsartan (Vals)FDA Link
01/2023 - 10/2018
4Interleukin-6 (Interleukin 6)IBA
01/2022 - 09/2016
4fibrin fragment D (D-dimer)IBA
07/2021 - 08/2006

Therapy/Procedure

105Therapeutics
05/2024 - 05/2002
15Catheters
01/2023 - 02/2006
8Patient Readmission
11/2023 - 01/2014
7Percutaneous Coronary Intervention
07/2023 - 02/2006
6Drug Therapy (Chemotherapy)
01/2023 - 05/2011
6Length of Stay
01/2022 - 03/2007
5Cardiac Resynchronization Therapy
08/2020 - 12/2014
4Coronary Artery Bypass (Coronary Artery Bypass Surgery)
10/2023 - 01/2003
4Mechanical Ventilators (Ventilator)
07/2021 - 09/2009